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Digital Health Market Insights - Winter 2025

Digital Health
Healthcare
Technology

Market Overview – Digital Health

  • After a quarter-over-quarter decline in Q3’25, global digital health equity funding rebounded in Q4’25, totaling $5.4B, representing a 12.5% quarter-over-quarter increase.
  • The funding environment continues to concentrate around scaled, later-stage platforms, with median pre-money valuations increasing to $31M in 2025 (from $26.5M in 2024) and average global digital health equity deal size rising to $20.3M (from $15.8M in 2024), as investors prioritize companies demonstrating clear product-market fit and revenue traction. This trend has been particularly pronounced among AI-enabled healthcare platforms, which continue to command valuation premiums and attract significant venture growth capital.
  • AI-enabled healthcare platforms remain the primary driver of investment activity, with capital increasingly directed toward clinical documentation, clinical decision support, provider workflow automation, and administrative efficiency solutions. Recent financings highlight this trend, including Ōura’s $907.7M Series E at an $11B valuation, OpenEvidence’s $200M raise at a $6B valuation, and Hippocratic AI’s $126M round at a $3.5B valuation, reflecting strong investor conviction in AI-native healthcare infrastructure and workflow platforms.
  • M&A activity moderated in Q4’25, with announced exits declining from 65 in Q3’25 to 36 in Q4’25. The largest transaction during the quarter was Thermo Fisher Scientific’s $8.88B acquisition of Clario, a provider of endpoint data solutions supporting clinical trials.
  • Overall, investors continue to view digital health as a structurally attractive market, with capital flowing toward segments where AI-driven automation can meaningfully reduce clinical and administrative burdens.

Sources: CB Insights; PitchBook

Bar chart showing average global digital health deal size across five periods, with the most recent period highlighted in gold indicating a recovery to near-peak levels after a mid-period decline.
Stacked bar chart showing the percent of quarterly digital health deals by region across five periods. The dominant region (gold) consistently accounts for roughly half of all deals, ranging from 49% to 56%. A second region (light gray) holds 17–19%, and a third region (dark gray) represents 18–26%, showing relative stability in regional deal share over time.

Subsector Spotlight: Longevity Tech

The longevity market encompasses therapeutics, diagnostics, digital platforms, and consumer solutions aimed at extending healthspan and preventing age-related disease. The market is driven by aging demographics, rising chronic disease burden, and advances in AI.

42%

Of the global population actively managing at least one chronic condition.

2.1 Billion+

People aged over 60 expected globally by 2050, up from ~1.4 billion today.

$47 Trillion

Projected cost of age-related chronic disease worldwide by 2030.

Overview

  • The traditional boundary between health care and beauty is narrowing as consumers increasingly demand scientifically validated products. Beauty and aesthetics companies are moving beyond purely cosmetic positioning and investing in biologically grounded claims to back new innovations.
  • Global aging trends are accelerating. Adults aged 60 and older now represent a significant share of the global population and are projected to exceed 2 billion people by 2050. This demographic shift is pressuring health systems, pension structures, and labor markets. In response, governments are increasingly framing longevity around health span.
  • Companies such as Function Health are gaining traction by positioning longevity around proactive diagnostics and continuous health monitoring. These platforms combine advanced lab testing, biomarker tracking, and personalized insights to identify risk before clinical disease manifests.

Sources: Deloitte; Mordor Intelligence; WHO; Founder Forum Group; HTF Market Intelligence

Bar chart showing the Global Longevity Tech Market projected to grow from 2024 to 2032 at a CAGR of 10.4%, with gold bars marking the 2024 actual baseline and near-term projections transitioning to gray bars through 2032.

The global longevity tech market was valued at $3.4B in 2024 and is projected to grow at a CAGR of 10.4%, reaching $7.5B by 2032

Longevity Platform Ecosystem

Advanced Diagnostics & Biomarker Testing

Early disease detection & biological age assessment through expanded biomarker panels & emerging diagnostic modalities

Examples:

  • Blood biomarker panels
  • Oral microbiome testing
  • Inflammation & metabolic markers
  • Hormone & nutrient profiling

Genomics & Personalized Risk Profiling

Genetic and epigenetic testing platforms enabling personalized longevity planning and disease risk identification

Examples:

  • Genomic risk scoring
  • Epigenetic aging clocks
  • Pharmacogenomics
  • Personalized longevity testing

Metabolic Health Optimization

Pharmacologic and clinical interventions designed to reset metabolic health and reduce long-term disease risk

Examples:

  • GLP-1 therapies intended for metabolic reset
  • Management of Insulin resistance
  • Weight optimization
  • Cardiometabolic reduction

Peptide & Regenerative Medicine

Emerging therapeutic modalities targeting cellular repair, inflammation reduction, and performance optimization

Examples:

  • Peptide therapies (BPC-157, thymosin, growth hormones secretagogues)
  • NAD+ therapies
  • Stem cell treatments
  • Regenerative injections

Continuous Biometric Monitoring

Wearable devices and connected diagnostics enabling real-time health tracking and longitudinal health data collection

Examples:

  • Oura Ring
  • Withings smart scale
  • CGM monitoring
  • Sleep and HRV tracking

AI-Driven Longevity Coaching

AI-enabled platforms that analyze biomarker, genomic, and wearable data to deliver personalized health optimization programs

Examples:

  • Nutrition & lifestyle optimization
  • Personalized treatment protocols
  • Continuous health feedback loops